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In onesurvey, the majority of PICUs in the UK utilizedSIMV in the management of this populationthough no well designed randomized controlledtrials corroborated the effectiveness of this mode(Manczur et al

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2008) while no such effect was observedhave provided positive results on alveolariza- after surgical ligation (Chang et al. Although no data are available on the frequency of AID deficiency, thisdisorder is estimated to affect fewer than 1 in 1000000 individuals

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